SantoTolling® is built to support complex chemical manufacturing at scale.
SantoTolling® is a custom manufacturing and tolling service offered by SantoLubes® Manufacturing LLC. Proudly manufacturing in South Carolina, USA, and serving partners globally for decades, SantoLubes® Manufacturing has been at the forefront of specialty chemical manufacturing.
We provide contract manufacturing solutions tailored to the unique needs of industries including agriculture, electronics, food additives, automotive, aviation, lubricants, and more. Our infrastructure and equipment enable customers to augment and extend production capacity without the burden of building and maintaining it internally.
Our services are designed to reduce product development cycles, minimize capital expenditures, ensure timely delivery, and maintain strict quality control within established quality systems.
At-a-Glance Capabilities
Scale & InfrastructureOperate within a large-scale manufacturing environment built to support high-volume production and complex chemical processing. |
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Manufacturing CapabilitiesExecute synthesis, blending, and processing across a wide range of chemical systems and production requirements. |
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Reaction CapabilitiesHandle diverse and complex reaction pathways required for specialty chemical manufacturing. |
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Analytical & Quality ControlValidate product consistency and maintain strict quality standards through continuous monitoring and advanced analytical methods. |
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Certifications & StandardsOperate within established quality and regulatory frameworks to ensure consistency, compliance, and reliability. |
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Industries ServedSupport a wide range of industries with tailored manufacturing solutions aligned to specific application requirements. |
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Industries ServedSupport a wide range of industries with tailored manufacturing solutions aligned to specific application requirements. |
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Manufacturing at Scale
Built to support demanding production requirements.
Producing and Supplying Up to 1.2 Billion Pounds Annually Worldwide 1
Operating on a Vast 66-Acre Facility Site With Over a Dozen Specialized Buildings
Outfitted with 19 Reactors, 33 Vessels, 67 Tanks, and More
Why SantoTolling





Comprehensive Services & Capabilities
SantoTolling® excels in synthesizing and blending a broad spectrum of chemicals, tailored to meet specific project needs.
These capabilities support a wide range of applications across industrial and specialty chemical markets.

Additives:

Pesticides:

Lubricants:

Polymers:

Surfactants:
These capabilities support a wide range of applications across industrial and specialty chemical markets.
How We Support Your Project
As a fully equipped facility, including pilot reactors, we support you from initial development to final delivery. We provide warehousing and bulk storage for a wide range of chemicals, helping shorten lead times, reduce costs, and optimize product quality.
This approach supports development, scale-up, and full production within a single operational environment, reducing complexity across project stages.
Technological & Process Excellence
State-of-the-Art Manufacturing Facilities
Enable complex chemistry to move from concept to full-scale production within a single, fully equipped manufacturing environment.
- Anhydrous HCl Column
- Dispersion Mixers & Grinders
- Distillation Columns (12, 15 & 30 trays)
- Glass-Lined Reactors (300 - 4,000 gal.)
- Homogenizers
- Rotary Vacuum Dryer
- Spray Dryers (Aqueous)
- Stainless Steel Reactors (300 - 12,000 gal.)
- Venturi Mixers - Gas/Liquid
- Wiped Film Evaporator
Analytical Capabilities
Ensure every batch meets defined specifications through continuous validation and quality control.
- Chromatography (Gas)
- FTIR/IR Spectroscopy
- Karl-Fischer (KF) Water Analysis
- Mass Spectrometry, Including LC-MS & GC-MS
- Nuclear Magnetic Resonance (NMR)
- Particle Size Analysis (Laser Diffraction)
- Potentiometric Titration
- Surface Tension
- UV-Vis
- Viscosity Measurement
- Wet Titration
Reaction Capabilities
Handle diverse and complex reaction pathways required for specialty chemical manufacturing.
- Alkoxylation
- Alkylation
- Amidation
- Anhydrous Ammonia Gases
- Boron Trifluoride
- Bulk Epichlorohydrin
- Chlorine
- Chloromethylation
- Condensation
- Diazotization
- Epichlorohydrin Reactions
- Esterification
- General Synthesis
- Hydrogenation
- Polymerization
- Quaternization (Methyl & Benzyl Chloride)
- Reductive Amination
- Transesterification
- Triethanolamine Reactions
- Trimethylamine Reactions
Processing Capabilities
Control pressure, temperature, and vacuum conditions to support precise, repeatable chemical processing.
- Pressure (to 500 psig)
- Temperature (-15 to 300°C)
- Vacuum (down to 10 mm Hg)

Expertise
Apply technical experience and process discipline to optimize performance, efficiency, and consistency.
- Expert Team: Highly qualified chemists, engineers, and professionals
- Registrations: ISO 9001-2015, ChemSteward, EPA Establishment, FIFRA Registered, Halal Certified, Kosher Certified, and more
- Quality Assurance: Fully staffed quality control lab operating 24 hours a day
- Industries Served: From textiles to oil & gas, petrochemical, lubricants, and more
- Six-Sigma Certified Black Belts: Ensure process optimizations and enhanced quality

Built for Large Scale
Deliver the capacity and infrastructure required to support large-scale manufacturing without compromise.
- Producing and Supplying Up to 1.2 Billion Pounds Annually Worldwide 1
- Operating on a Vast 66-Acre Facility Site With Over a Dozen Specialized Buildings
- Outfitted with 19 Reactors, 33 Vessels, 67 Tanks, and More
Ready to Bring Your Vision to Life?
Let SantoTolling be your partner in manufacturing success.
Schedule Your Free Consultation

What to Expect:
- Submit your project details
- Initial review and alignment
- Technical discussion and feasibility
- Next steps for pilot or production

